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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
42.42
Human Site:
Y453
Identified Species:
71.79
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
Y453
E
L
Y
R
A
T
F
Y
A
A
E
I
M
C
G
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y484
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y917
E
L
Y
R
A
T
F
Y
A
A
E
I
I
C
G
Dog
Lupus familis
XP_849292
706
81555
Y484
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
Y451
E
L
Y
R
A
T
F
Y
A
A
E
I
I
C
G
Rat
Rattus norvegicus
P09215
673
77502
Y451
E
L
Y
R
A
T
F
Y
A
A
E
I
I
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y486
E
L
V
R
A
T
F
Y
A
A
E
I
I
C
G
Chicken
Gallus gallus
NP_001006133
699
80179
Y461
D
L
Y
R
A
T
F
Y
G
A
E
I
L
C
G
Frog
Xenopus laevis
NP_001084460
683
78181
Y460
D
L
Y
R
A
T
F
Y
A
S
E
I
I
C
G
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
L378
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
Y447
S
E
E
R
A
R
F
Y
G
A
E
I
I
S
G
Honey Bee
Apis mellifera
XP_394743
624
71014
Y406
P
E
P
R
A
R
F
Y
A
A
E
I
W
S
G
Nematode Worm
Caenorhab. elegans
P34722
704
80280
Y479
D
E
A
R
T
R
F
Y
A
C
E
I
V
V
A
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
I382
F
L
H
K
R
G
I
I
Y
R
D
L
K
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
73.3
93.3
73.3
N.A.
93.3
93.3
N.A.
86.6
80
80
6.6
N.A.
53.3
60
40
6.6
P-Site Similarity:
100
86.6
100
86.6
N.A.
100
100
N.A.
93.3
93.3
100
13.3
N.A.
60
60
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
79
0
0
0
72
72
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
50
0
% C
% Asp:
36
0
0
8
0
0
0
0
8
0
8
0
0
0
8
% D
% Glu:
36
22
8
0
0
0
0
0
0
0
93
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
15
0
0
8
0
0
79
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
0
86
58
8
0
% I
% Lys:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
8
% K
% Leu:
8
72
8
0
0
0
8
8
0
0
0
8
8
22
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
86
8
22
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
15
0
0
0
0
0
0
15
0
0
0
15
0
% S
% Thr:
0
0
0
0
8
65
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
8
0
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
43
0
0
0
0
86
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _